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Stem Cell
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Research group for stem cells & tissue engineering Introduction The research group for stem cells and tissue engineering has been the first group developed in Stem Technology Company beginning its research work early in establishment of the company. The specialists working in this research group, mainly from basic medical sciences fields such as hematology, immunology, biochemistry, medical biotechnology and other specialties, are engaged in various fields related to stem cell research with proper organization. This group has close contacts with other research groups to achieve short and long term goals of the complex. Nanoscaffolds required for cell culture are assembled by biometrial and nanotechnology groups based on desired parameters, and are used for various transplantation practices after being evaluated through diverse tests for biological properties in laboratory environment. Collaboration of molecular biology and genetics engineering groups for molecular confirmation of the engineered tissues is essential and is an important strength point of this company to attain its goals. The most important research topics of this group are as follows: 1.Study of biology of stem cell types including embryonic stem cells, mesenchymal stem cells, unrestricted somatic stem cells, hematopoietic stem cells and tissue specific stem cells from various biological sources including umbilical cord blood, bone marrow and different tissues of human, mouse and rat. 2. Bone tissue engineering aiming at applications in repair of bone injuries 3. Skin tissue engineering aiming at future applications in burns and cosmetic uses 4. Liver tissue engineering using concurrent use of stem cells and appropriate nanoscaffolds 5. Design and work with specific bioreactors for three dimensional culture, proliferation and differentiation of stem cells in controlled conditions 6. Three dimensional culture of stem cells and their differentiated products on biocompatible and biodegradable scaffolds made by biometrial and nanotechnology groups with trade mark NanoECM and other newly designed scaffolds and evaluation of the cell behavior 7. Nuclear transfer in mouse model as primary model to achieve cloning therapy 8. Production of transgenic mice with the ultimate goal of producing transgenic products |
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